NMD-VCell Research Workbench Module: Compare genes · evidence-to-experiment workflow NMD = neuromuscular disorders
Search Release v1.0 candidate
Governance ▾
Scientific program No-new-wet-lab evaluation Methods Claim boundary Benchmarks v1 release gate v1 authorization Prediction gate Registry Transitions Maintenance
v1.0 candidate Frozen 25 Jul 2026 DOI pending
v1.0.0-database-resource Schema 1.1 Model ridge-safe-v2.3 Benchmark repeated-fold-v2.2 Build EA-20260729-18 v1.0 is a database and evidence-governance release; it is not a validated disease-prediction or clinical decision-support release.
Research evidence only Observed HepG2 perturbations with limited external myogenic context No validated DMD perturbation prediction Evidence boundary

Compare genes

Compare genes

One matrix, separate evidence dimensions

Paste up to 500 HGNC symbols, aliases, previous symbols, Ensembl Gene IDs, NCBI Gene IDs or HGNC IDs. The atlas preserves mapping provenance and never silently resolves ambiguity.

Interpretation“Not assessed” is not a negative result. Historical ranks are excluded from the default comparison.

Evidence comparison

Default worked example

ZNF133 · MON1A · GFOD2 rendered on page open

These rows are server-rendered from the frozen comparison object CMP-20260726-A9A727B87722. Editing the textarea reruns the interactive comparator.

No ranking generated

Default comparison visual dashboard

Evidence contrast at a glance

Default genes are shown in the frozen comparison order; no clustering, score or rank is generated.

No ranking generated
3input rows
3mapped records
2action classes
2gap classes
2L3a assessed
3muscle TPM ≥ 1
Evidence contrast matrixRows preserve the input/default order; colors encode field state only.
ZNF133 Muscle-context assay
L2Observed DMDConflicted Agreement3/4 Muscle4.56 TPM L3aAssessed · no current hit GapGAP-02
MON1A Muscle-context assay
L2Observed DMDConflicted Agreement2/4 Muscle8.06 TPM L3aAssessed · no current hit GapGAP-02
GFOD2 Provisional hold · external report not yet audited
L2Observed DMDConflicted Agreement2/4 Muscle2.95 TPM L3aNot assessed GapGAP-09
Gap contrastDecision-blocking gap count across mapped genes.
GAP-02Independent muscle-context perturbation is absent 2
GAP-09External quantitative evidence has not been imported and audited 1

Interpretation boundary: this comparison view separates evidence dimensions. It does not compute a winner, cluster, target score, therapeutic priority or disease-prediction claim.

Evidence matrix

Default three-gene example; input order preserved
GeneActionEvidenceDMD stateGapNext object
ZNF133 Muscle-context assay L2 observed same context perturbation Conflicted GAP-02 Open Study Card
MON1A Muscle-context assay L2 observed same context perturbation Conflicted GAP-02 Open Study Card
GFOD2 Provisional hold · external report not yet audited L2 observed same context perturbation Conflicted GAP-09 Open Study Card

Source comparison

GeneLegacy integrated DMD priorSource agreementMuscle expressionL3a screen
ZNF133 up 3/4 4.56 TPM Assessed · no current hit
MON1A up 2/4 8.06 TPM Assessed · no current hit
GFOD2 up 2/4 2.95 TPM Not assessed

Decision comparison

Natural-language summary: ZNF133 and MON1A share the same next action—an independent myogenic perturbation assay—whereas GFOD2 remains on hold until its reported external evidence is imported and audited.

Evidence differences: main blocking gaps differ across 2 gap codes.

No composite score, rank, treatment recommendation or disease-prediction claim is generated.