NMD-VCell Research Workbench Module: Validate / registry · evidence-to-experiment workflow NMD = neuromuscular disorders
v1.0 candidate Frozen 25 Jul 2026 DOI pending
v1.0.0-database-resource Schema 1.1 Model ridge-safe-v2.3 Benchmark repeated-fold-v2.2 Build EA-20260729-15 v1.0 is a database and evidence-governance release; it is not a validated disease-prediction or clinical decision-support release.
Current evidence ceiling L2 observed HepG2 limited L3a context No independent DMD perturbation validation Open boundary

V1ReleaseGate · v1 final-release freeze candidate

Internal gates pass; formal v1.0 remains locked until external authorization.

v1.0 is a database and evidence-governance release; it is not a validated disease-prediction or clinical decision-support release.

v1 final release freeze candidateOnly after all four external gates are structurally complete and author/institution authorization is recorded may the site label be changed to formal v1.0. That change still does not unlock P1 or P2 prediction claims.

Gate summary

What is complete now?

Internal public-object gates10/10 pass
External gates complete0/4
Formal v1.0 releaseLOCKED
Prediction claim stateP0 prediction infrastructure ready P1 unvalidated P2 locked

Automated gates

Internal gates

GateStatusEvidenceMeaning
single_source_release_identitypassapi/v1.1/release_manifest.jsonInternal release-object integrity gate
analysis_core_archive_checksumpasschecksums.sha256Internal release-object integrity gate
sqlite_integrity_and_nonempty_tablespassdownloads/large_assets/nmd_vcell_sqlite_v0.9.2_schema1.1_20260725.sqlite/parts_manifest.tsvInternal release-object integrity gate
typed_canonical_apipassapi/v1.1/openapi.jsonInternal release-object integrity gate
bounded_candidate_decision_statepassapi/v1.1/genes/GFOD2.jsonInternal release-object integrity gate
v1_release_freeze_gatepassapi/v1.1/v1_release_gate.jsonInternal release-object integrity gate
prediction_registry_scaffoldpassapi/v1.1/prediction_registry.jsonInternal release-object integrity gate
database_paper_policy_packagepassdownloads/DATABASE_PAPER_READINESS.mdInternal release-object integrity gate
external_authorization_dossier_packagepassdownloads/V1_EXTERNAL_AUTHORIZATION_DOSSIER.mdInternal release-object integrity gate
evidence_atlas_overlay_archive_checksumpassapi/v1.1/overlay_archive_identity.jsonInternal release-object integrity gate

External gates

Pending inputs

GateStatusRequired inputOwner
permanent_doi_archivepending_external_actionDOI for the unchanged canonical archiveExternal author/institution action
institution_approved_data_licencepending_institutional_approvalApproved data licence identifier and textExternal author/institution action
approved_code_licencepending_institutional_approvalApproved code licence identifier and textExternal author/institution action
final_maintainer_and_institution_metadatapending_author_inputApproved maintainer, affiliation and contact metadataExternal author/institution action

Database-paper package

Objects that must move together

Publication package

  • api/v1.1/release_manifest.json
  • api/v1.1/openapi.json
  • api/v1.3/research-objects/registry.json
  • api/v1.1/v1_release_gate.json
  • api/v1.1/v1_external_authorization_dossier.json
  • api/v1.1/prediction_registry.json
  • ro-crate-metadata.json
  • codemeta.json
  • checksums.sha256
  • downloads/nmd_vcell_data_dictionary_schema_1.1.tsv
  • downloads/DATABASE_PAPER_READINESS.md
  • downloads/NAR_DATABASE_CHECKLIST.md
  • downloads/DATA_AVAILABILITY.md
  • downloads/MAINTENANCE_POLICY.md
  • downloads/VERSIONING_POLICY.md
  • downloads/V1_EXTERNAL_AUTHORIZATION_DOSSIER.md
  • downloads/v1_deposit_manifest.json
  • downloads/v1_deposit_file_list.tsv
  • downloads/v1_authorization_checklist.tsv
  • downloads/v1_licence_maintainer_metadata_template.tsv
  • downloads/prediction_card.schema.json
  • downloads/outcome_board.schema.json
  • downloads/external_validation_import_template.json
  • downloads/v1_release_handoff_checklist.tsv
  • downloads/V1_EXTERNAL_GATE_HANDOFF.md
  • downloads/v1_external_gate_input_template.json
  • downloads/validate_v1_external_gates.py

Still not authorized

  • formal v1.0 wording before DOI/licence/maintainer gates pass
  • validated DMD disease prediction
  • clinical decision support
  • therapeutic or treatment-prioritization claims
Release discipline. The gate can authorize database-resource wording only. It cannot unlock P1/P2 prediction claims; those remain governed by PredictionReadiness and the empty prediction registry.