NMD-VCell Research Workbench Module: Compare genes · evidence-to-experiment workflow NMD = neuromuscular disorders
Search Release v1.0 candidate
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Scientific program Methods Claim boundary Benchmarks v1 release gate v1 authorization Prediction gate Registry Transitions Maintenance
v1.0 candidate Frozen 25 Jul 2026 DOI pending
v1.0.0-database-resource Schema 1.1 Model ridge-safe-v2.3 Benchmark repeated-fold-v2.2 Build EA-20260729-15 v1.0 is a database and evidence-governance release; it is not a validated disease-prediction or clinical decision-support release.
Current evidence ceiling L2 observed HepG2 limited L3a context No independent DMD perturbation validation Open boundary

Released comparison object · v1.0.0-database-resource

Computational-replication queue

3 mapped genes · immutable · no ranking generated

Object IDCMP-20260726-61BB5BEE5251
LifecycleRELEASED
Gene schema1.1
Object buildEA-20260726-13
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Preserved evidence dimensions

Input order preserved; actions and gaps are not collapsed into a composite score
GeneCurrent actionHighest supportedLegacy integrated DMD priorSource agreementDecision-blocking gap
INTS13 Risk/context review L2 observed same context perturbation up 4/4 GAP-08 Safety and dependency context blocks escalation
NAGLU Risk/context review L2 observed same context perturbation up 3/4 GAP-08 Safety and dependency context blocks escalation
RNF8 Risk/context review L2 observed same context perturbation up 2/4 GAP-08 Safety and dependency context blocks escalation
Claim boundary. This comparison preserves evidence dimensions and missingness. It does not create a composite score, ranking, causal claim or therapeutic recommendation.
Cite this comparison

Object ID: CMP-20260726-61BB5BEE5251

Payload SHA-256: 61bb5bee525128e470584b8361eadf2be2619411594f77457061c90d431a009a. Stable URL: https://nmd-vcell.sema3c.chatgpt.site/resource/comparison/CMP-20260726-61BB5BEE5251/.