NMD-VCell Research Workbench Module: Compare genes · evidence-to-experiment workflow NMD = neuromuscular disorders
Search Release v1.0 candidate
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Scientific program Methods Claim boundary Benchmarks v1 release gate v1 authorization Prediction gate Registry Transitions Maintenance
v1.0 candidate Frozen 25 Jul 2026 DOI pending
v1.0.0-database-resource Schema 1.1 Model ridge-safe-v2.3 Benchmark repeated-fold-v2.2 Build EA-20260729-15 v1.0 is a database and evidence-governance release; it is not a validated disease-prediction or clinical decision-support release.
Current evidence ceiling L2 observed HepG2 limited L3a context No independent DMD perturbation validation Open boundary

Released comparison object · v1.0.0-database-resource

Mixed action and gap comparison

4 mapped genes · immutable · no ranking generated

Object IDCMP-20260726-1DF261243518
LifecycleRELEASED
Gene schema1.1
Object buildEA-20260726-13
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Preserved evidence dimensions

Input order preserved; actions and gaps are not collapsed into a composite score
GeneCurrent actionHighest supportedLegacy integrated DMD priorSource agreementDecision-blocking gap
ZNF133 Muscle-context assay L2 observed same context perturbation up 3/4 GAP-02 Independent muscle-context perturbation is absent
WDR4 Risk/context review L2 observed same context perturbation up 4/4 GAP-08 Safety and dependency context blocks escalation
GFOD2 Provisional hold · external report not yet audited L2 observed same context perturbation up 2/4 GAP-09 External quantitative evidence has not been imported and audited
INTS13 Risk/context review L2 observed same context perturbation up 4/4 GAP-08 Safety and dependency context blocks escalation
Claim boundary. This comparison preserves evidence dimensions and missingness. It does not create a composite score, ranking, causal claim or therapeutic recommendation.
Cite this comparison

Object ID: CMP-20260726-1DF261243518

Payload SHA-256: 1df2612435184031f398d71ed552ed8cb9afeb2934af2cab9c24eef8aab97773. Stable URL: https://nmd-vcell.sema3c.chatgpt.site/resource/comparison/CMP-20260726-1DF261243518/.